Application of MRI in the Differential Diagnosis of Focal Organizing Pneumonia and Peripheral Lung Cancer
Objective:To explore the value of magnetic resonance imaging(MRI)in the differential diagnosis of focal organizing pneumonia(FOP)and peripheral lung cancer(PLC).Methods:A retrospec-tive analysis was performed on the clinical data of 60 patients with PLC(PLC group)and 60 patients with FOP(FOP group)in the hospital between December 2022 and December 2023.The general data[age,gender,body mass index(BMI),smoking history]and MRI signs[morphological characteristics(spicule sign,lobulation sign,vacuole sign,pleural indentation sign,abscess formation,mediastinal lymph node enlargement),apparent diffusion coefficient(ADC),maximum diameter and sites of lesions]were com-pared between the two groups.The diagnostic value of relevant parameters in PLC patients was analyzed by ROC curves.Results:The proportions of spicule sign,lobulation sign,vacuole sign,abscess formation and mediastinal lymph node enlargement in PLC group were higher than those in FOP group,while the ADC value was lower in the PLC group compared to the FOP group(P＜0.05).The results of ROC curves analysis showed that spicule sign(AUC=0.658),mediastinal lymph node enlargement(AUC=0.642)and low ADC(AUC=0.758)were of diagnostic value for PLC,and diagnostic value of combined detection was higher(AUC=0.767,P＜0.05).Conclusion:Spicule sign,mediastinal lymph node enlargement and low ADC can be applied as indexes in the differential diagnosis of PLC and FOP,and diagnostic value of com-bined detection is higher.
Magnetic resonance imagingFocal organizing pneumoniaPeripheral lung cancerDif-ferential diagnosis
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