医学理论与实践2025,Vol.38Issue(1) :34-37.DOI:10.19381/j.issn.1001-7585.2025.01.007

入ICU 12h内相关指标构建危重症患者预后预测模型

The Prognostic Model of Critically Ill Patients was Established within 12 Hours after Admission to ICU

李淑娴 翁慧纯 洪春燕
医学理论与实践2025,Vol.38Issue(1) :34-37.DOI:10.19381/j.issn.1001-7585.2025.01.007

入ICU 12h内相关指标构建危重症患者预后预测模型

The Prognostic Model of Critically Ill Patients was Established within 12 Hours after Admission to ICU

李淑娴 1翁慧纯 1洪春燕1
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作者信息

  • 1. 广东省汕头市中心医院重症医学科 515031
  • 折叠

摘要

目的:探讨危重症患者28d死亡的影响因子,以入ICU 12h内指标构建危重症患者预后预测模型.方法:回顾性分析2021年1月-2022年6月我院ICU接收的危重症患者资料,经多因素二元logistic回归模型筛选影响因子,构建预测模型,并采用Nomogram模型展示影响因子对预后影响可视化.结果:共纳入259例危重症患者,入ICU 28d存活180例,死亡79例.多因素logistic回归分析显示年龄(OR=1.021,95%CI:1.002~1.040)、收缩压(OR=0.990,95%CI:0.981~0.999)、血清肌酐(OR=1.142,95%CI:1.018~1.281)、氧合指数(OR=0.998,95%CI:0.996~1.000)、格拉斯哥昏迷评分(OR=0.992,95%CI:0.868~0.981)是危重症患者28d死亡的影响因子(P<0.05);建立危重症患者 28d 死亡的预测模型为 P=1/(1+e-z),Z=0.021 ×年龄-0.010 × SBP+0.133 × SCr-0.002 × OI-0.081 ×GCS,该模型对危重症患者预后预测AUC为0.752(95%CI:0.685~0.819,P<0.001),敏感度为0.658,特异度为0.767.结论:入ICU 12h内的年龄、收缩压、血清肌酐、氧合指数、格拉斯哥昏迷评分是本组危重症患者28d死亡的影响因子,依托入ICU 12h内建立的预测模型在早期预测危重症患者有良好的价值.

Abstract

Objective:To explore the influencing factors of 28-day death in critically ill patients,and to build a prognostic model of critically ill patients with indicators within 12 hours after admission to ICU.Methods:The data of critically ill pa-tients were received from the ICU of our hospital from January 2021 to June 2022 were analyzed retrospectively.The influen-cing factors were screened by multivariate binary logistic regression model,and a prediction model was constructed to visualize the influence of influencing factors on prognosis by Nomogram model.Results:A total of 259 critically ill patients were includ-ed,of whom 180 survived and 79 died after 28 days in ICU.The multivariate logistic regression analysis showed that age(OR=1.021,95%CI:1.002~1.040),systolic blood pressure(OR=0.990,95%CI:0.981~0.999),serum creatinine(OR=1.142,95%CI:1.018~1.281),oxygenation index(OR=0.998,95%CI:0.996~1.000),Glasgow coma score(OR=0.992,95%CI:0.868~0.981)were the influential factors for 28-day death in critically ill patients(P<0.05).The prediction model of 28-day death in critically ill patients was established as P=1/(1+e-z),Z=0.021 x age-0.010 x SBP+0.133 x SCr-0.002 x O1-0.081 x GCS.The predictive AUC of this model for critically ill patients was 0.752(95%CI:0.685~0.819,P<0.001),sensitivity was 0.658,and specificity was 0.767.Conclusion:Age,systolic blood pressure,serum creatinine,oxygenation index and Glasgow coma score within 12 hours of ICU admission are the influ-ential factors for 28-day death of critically ill patients in this study.The predictive model established within 12 hours of ICU admission has good value in early prediction of critically ill patients.

关键词

危重症患者/重症监护室/12h内相关指标/预测模型

Key words

Critically ill patients/Intensive care unit/indicators within 12 hours index/Prediction model

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出版年

2025
医学理论与实践
河北省预防医学会 河北省药学会

医学理论与实践

影响因子:0.746
ISSN:1001-7585
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