Research advances of pentacyclic triterpenoid natural products
Pentacyclic triterpenoids are a class of widespread natural compounds containing six isoprene structures with a wide range of pharmacological activities,including antibacterial,anti-inflammatory,antiviral,antitumor,immune regulation,etc.The structural modifications of pentacyclic triterpenoid natural products and the drug development have always been a hot research topic.This article reviews the recent progresses in the structural modifications,pharmacological effects,and clinical studies of different kinds of pentacyclic triterpenoid natural products.