摘要
研究多裂黄檀Dalbergia rimosa Roxb.根茎的化学成分.采用硅胶、MCI和Sephadex LH-20柱色谱以及半制备高效液相色谱等技术进行分离纯化,通过波谱数据鉴定化合物结构.从多裂黄檀根茎的乙酸乙酯部位中分离得到13个化合物,分别鉴定为多裂异黄酮A、B(1和2)、刺芒柄花素(3)、7,4'-二甲氧基异黄酮(4)、4',6,7-trimethoxyisoflavone(5)、鹰嘴豆芽素 A(6)、樱黄素(7)、7-O-methyltectorigenin(8)、3'-hydroxydaidzein(9)、orobol 7,3'-dimethyl ether(10)、2',7-dihydroxy-4',5'-dimethoxyisoflavone(11)、pruinosanone E(12)、caviunin(13).其中,化合物1和2为新化合物,化合物3～13为首次从该植物中分离得到.化合物9和11对DPPH自由基有显著清除作用.
Abstract
Studies on chemical constituents in the rhizome of Dalbergia rimosa Roxb.The chemical constituents from the ethyl acetate part of D.rimosa were isolated and purified by silica gel,MCI gel,Sephadex LH-20 gel and semi-preparative HPLC,and the stuctures were identified by spectral method.Thirteen compounds were isolated from the ethyl acetate part of the rhizome of D.rimosa and identified as dalbergiaisoflavones A,B(1,2),formononetin(3),7,4'-dimethoxyisoflavone(4),4',6,7-trimethoxyisoflavone(5),biochanin A(6),prunetin(7),7-O-methyltectorigenin(8),3'-hydroxydaidzein(9),orobol 7,3'-dimethyl ether(10),2',7-dihydroxy-4',5'-dimethoxyisoflavone(11),pruinosanone E(12),caviunin(13).Compounds 1 and 2 are new compounds,and compounds 3-13 were isolated from this plant for the first time.Compounds 9 and 11 had remarkable scavenging effect on DPPH free radicals.
基金项目
广西自然科学基金资助项目(2023JJA140637)
国家重点研究计划项目(2019YFC17123012)
广西科技基地和人才专项(桂科AD20238058)
广西中医药管理局科研课题(GXZYA20220122)
广西一流学科建设开放课题自然科学项目(2019XK129)
广西壮瑶药重点实验室开放课题(GXZY22.2019-10)
NETL
NSTL
万方数据