摘要
利用硅胶、Sephadex LH-20和Toyopearl HW-40C等柱色谱及半制备液相等分离纯化方法,从杜仲中分离得到11个化合物.运用现代波谱学方法确定化合物的结构,分别鉴定为neoeucommiate A(1)、(7S,8R)-dihydrodehydrodiconiferyl alcohol(2)、urolignoside(3)、ficusal(4)、tiruneesiin(5)、glochidioboside(6)、forsythialansides B(7)、ecdysanol B(8)、(+)-syringaresinol-4-O-β-D-glucopyranoside(9)、(+)-pinoresinol-4-O-[6"-O-vanilloyl]-β-D-glucopyranoside(10)和samsesquinoside(11).其中化合物1为新化合物,化合物3～7、10、11为首次从杜仲中分离得到.
Abstract
Eleven compounds were isolated from Eucommia ulmoides by silica gel,Sephadex LH-20,HW-40C column chromatography and semi-preparative HPLC.Their structures were identified by modern spectroscopic methods as neoeucommiate A(1),(7S,8R)-dihydrodehydrodiconiferyl alcohol(2),urolignoside(3),ficusal(4),tiruneesiin(5),glochidioboside(6),forsythialansides B(7),ecdysanol B(8),(+)-syringaresinol-4-O-β-D-glucopy-ranoside(9),(+)-pinoresinol 4-O-[6"-O-vanilloyl]-β-D-glucopyranoside(10),samsesquinoside(11).Compound 1 is a new compound,compounds 3-7,10 and 11 were isolated from Eucommia ulmoides for the first time.
基金项目
中央引导地方科技发展专项资金([2016]149)
河南省高层次人才特殊支持计划(ZYQR201810080)
NETL
NSTL
万方数据