运用MCI Gel CHP20P、SephadexLH-20、ODS和硅胶等柱色谱，结合TLC、半制备液相色谱等分离纯化方法，从苏合香水提物的95％乙醇溶解物中得到12个松香烷二萜化合物。运用1D、2D NMR、UV、MS等现代波谱学方法对所分离得到的化合物进行结构鉴定，并运用计算ECD的方法确定了新化合物的绝对构型。其中，化合物1为新化合物，鉴定为(4R，5R，9S，10R，12S)-12-methoxy-neoabietic acid，化合物2～12为首次从苏合香中分离得到。
A new abietane diterpene from the Styrax
Twelve abietane diterpenes were isolated from the 95％ethanol fraction solvated from the aqueous extract of Styrax by using various chromatographic methods,including MCI Gel CHP 20P,Sephadex LH-20,ODS,silica gel,TLC and semi-preparative HPLC.The structures of the isolated compounds were identified by spectroscopy methods(1D,2D NMR,UV,MS,etc.),and the absolute configuration of the new compound was determined by ECD calculations.Compound 1 is a new compound,which was identified as(4R,5R,9S,10R,12S)-12-methoxy-neoabietic acid,and compounds 2-12 were isolated from Styrax for the first time.
Styraxresinabietane diterpenesextraction and separationstructural identification
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