Effect Observation of Jiawei Erchen Decoction Combined with Chemotherapy in the Treatment of Non-small Cell Lung Cancer
Objective To study the clinical effect of Jiawei Erchen decoction combined with chemotherapy in the treatment of patients with non-small cell lung cancer(NSCLC).Methods A total of 62 patients with NSCLC admitted to the Department of Oncology,Yugan County People's Hospital from March 2019 to March 2022 were selected and divided into control group(31 patients)and observation group(31 patients)according to the random number table method.The control group was treated with chemotherapy,and the observation group was treated with Jiawei Erchen decoction on the basis of the control group.The short-term efficacy,TCM symptom score,tumor marker levels[carcinoembryonic antigen(CEA),squamous cell carcinoma-associated antigen(SCC)],adverse reactions,Karnofky Performance Status(KPS)score,and Functional Assessment of Cancer Therapy-Lung(FACT-L)scale score were compared between the two groups.Results The disease control rate and objective remission rate of the observation group were higher than those of the control group(P＜0.05).After treatment,the scores of TCM symptoms in the two groups were lower than those before treatment,and the scores of TCM symptoms in the observation group were lower than those in the control group(P＜0.05).After treatment,the levels of CEA and SCC in the two groups were lower than those before treatment,and the levels of CEA and SCC in the observation group were lower than those in the control group(P＜0.05).The KPS and FACT-L scores of the two groups after treatment were higher than those before treatment,and the KPS and FACT-L scores of the observation group were higher than those of the control group(P＜0.05).The incidence of adverse reactions in the observation group was lower than that in the control group(P＜0.05).Conclusion Jiawei Erchen decoction combined with chemotherapy has an ideal short-term effect in the treatment of NSCLC,which can further alleviate the symptoms of patients,down-regulate the level of tumor markers,reduce adverse drug reactions,and help to improve the health status and quality of life of patients.
Non-small cell lung cancerJiawei Erchen decoctionQuality of lifeTumor markers
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