Value of Combined Test of Serum C Peptide and Glycosylated Hemoglobin in the Auxiliary Diagnosis of Diabetic Mellitus Patients
Objective To study the value of combined test of serum C peptide and glycosylated hemoglobin in the auxiliary diagnosis of diabetic mellitus patients.Methods From March 2020 to January 2023,forty-six diabetic patients diagnosed and treated in our hospital from were selected as the observation group,and during the same period,46 healthy people who underwent physical examination in our hospital were selected as the control group.The blood glucose levels and serum C-peptide levels in the control group and the observation group,as well as the diabetic patients with and without complications were compared,and the diagnostic efficacy of different indicators for diabetes was analyzed,as well as the relationship between serum C-peptide,glycosylated hemoglobin and diabetic complications.Results The levels of fasting blood glucose and 2 h postprandial blood glucose in the observation group were higher than those in the control group(P＜0.05).The level of serum C peptide in the observation group was lower than that in the control group,and the level of glycosylated hemoglobin was higher than that in the control group(P＜0.05).The sensitivity and specificity of serum C peptide+glycosylated hemoglobin in the diagnosis of diabetes mellitus were higher than those of serum C peptide and glycosylated hemoglobin(P＜0.05),but there was no significant difference in the sensitivity and specificity between serum C peptide and glycosylated hemoglobin(P＞0.05).The level of serum C peptide in patients with diabetes mellitus complicated with complications was lower than that in patients without diabetes mellitus complicated with complications,and the level of glycosylated hemoglobin was higher than that in patients without diabetes mellitus complicated with complications(P＜0.05).Pearson correlation analysis showed that diabetic complications were negatively correlated with serum C-peptide(r=-0.686,P＜0.05)and positively correlated with glycosylated hemoglobin(r=0.562,P＜0.05).Conclusion Serum C-peptide and glycosylated hemoglobin are closely related to the development of diabetic mellitus patients.The combined test can improve the diagnostic efficacy of diabetic mellitus patients,and assist the clinical judgment of blood glucose level,disease progression and complications to a certain extent,and provide a reliable reference for the diagnosis and treatment of diabetes mellitus and the prevention of diabetic complications.
万方数据
维普
