Application of Single Cell Sequencing in Gynecological Malignant Tumor
Gynecological malignant tumor is formed due to the high degree of heterogeneity of gynecological malignant tumor cells and the complex microenvironment,which is the main cause of death for women worldwide and seriously threatens the health of women worldwide.Single cell RNA sequencing(scRNA-seq)is a revolutionary new technology that amplifies and sequenced the genome or transcriptome at the level of a single cell.The most significant advantage is that it is more accurate and can capture rare genes and subsets,which are not accessible by traditional sequencing methods.Therefore,the use of this technology is helpful to deeply understand the occurrence and development mechanism of gynecological malignant tumors,discover new markers and potential therapeutic targets,and provide a theoretical basis for the precision treatment of patients with gynecological malignant tumors.This article mainly introduces the application of single-cell sequencing technology in cervical cancer,endometrial carcinoma and ovarian cancer.
Single cell sequencing technologyGynecological malignant tumorTumor microenvironmentHeterogeneity of tumor
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