首页|支气管哮喘与肠道菌群研究进展

支气管哮喘与肠道菌群研究进展

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支气管哮喘是一种慢性气道炎症性疾病,以可逆性气流变化和气道重塑为主要特征.近年来哮喘发病率呈现逐年上升的趋势,如何有效控制和预防该病成为目前国内外学者共同关注的热点问题.临床研究发现哮喘患者存在肠道菌群失调现象,同时肠道菌群亦可以影响哮喘的发生发展.本文就近年来肠道菌群与哮喘的相关研究进展进行综述,旨在通过阐述肠道菌群对支气管哮喘发病机制的影响进而明确肠道菌群在哮喘发生发展中的重要性,以期为哮喘的临床治疗及预防提供新思路.
Research Progress on Bronchial Asthma and Intestinal Flora
Bronchial asthma is a chronic inflammatory disease of the airways,characterised by reversible airflow changes and airway remodelling.The incidence of asthma has been on the rise year by year in recent years.How to effectively control and prevent the disease has become a hot issue of common concern among scholars at home and abroad.Clinical studies have found that patients with asthma have intestinal flora imbalance,and intestinal flora can also affect the occurrence and development of asthma.This article reviews the research progress of intestinal flora and asthma in recent years,aiming to clarify the importance of intestinal flora in the occurrence and development of asthma by expounding the influence of intestinal flora on the pathogenesis of bronchial asthma,in order to provide new ideas for the clinical treatment and prevention of asthma.

Bronchial asthmaIntestinal floraProbioticsShort-chain fatty acidsInnate lymphoid cells

于新鹤、黄燕、杨爽、包海鹏、赵丽萍、赵超

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内蒙古医科大学研究生院,内蒙古呼和浩特 010000

内蒙古自治区中医医院肺病科,内蒙古 呼和浩特 010000

支气管哮喘 肠道菌群 益生菌 短链脂肪酸 固有淋巴细胞

内蒙古自治区科技成果转化引导项目内蒙古自治区人才开发基金高层次人才个人项目内蒙古自治区卫生健康科技计划项目

2020CG01202021003017202201107

2024

医学信息
国家卫生部信息化管理领导小组 中国电子学会中国医药信息学分会 陕西文博生物信息工程研究所

医学信息

影响因子:0.161
ISSN:1006-1959
年,卷(期):2024.37(2)
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