Meta-analysis of the Incidence of Depression in Patients with Rheumatoid Arthritis in China
Objective To understand the incidence of depression in patients with rheumatoid arthritis in China,and to provide reference for clinical practice.Methods The literature on the incidence of depression in patients with rheumatoid arthritis in China published from the establishment of the database to February 2023 was searched in China Knowledge Network Infrastructure,Wanfang,VIP,SinoMed,PubMed and MedlineComplete databases.Two researchers independently screened literature to establish a database,and meta-analysis was performed using R4.2.2 software.Results A total of 40 literatures were included,and 4075 of 8535 patients with rheumatoid arthritis were found to have depressive symptoms.The incidence of depression in Chinese patients with rheumatoid arthritis was 44.70%(95%CI:38.90-50.44).The results of subgroup analysis showed that the incidence of depression in female patients[28.52%(95%CI:20.22-38.58)]was higher than that in male patients[6.78%(95%CI:4.92-9.27)],and the difference was statistically significant(P=0.0002).There was a statistically significant difference in the incidence of depression measured by different assessment tools(P<0.0001).Conclusion The incidence of depression in patients with rheumatoid arthritis in China is high.It is necessary to pay attention to the psychological state of patients and take intervention measures to provide effective support.