首页|中国类风湿关节炎患者抑郁发病率的Meta分析

中国类风湿关节炎患者抑郁发病率的Meta分析

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目的 了解我国类风湿关节炎患者抑郁发病率,为临床提供参考意见。方法 检索中国知网、万方、维普、中国生物医学文献服务系统、PubMed、MedlineComplete数据库中建库至2023年2月发表的中国类风湿关节炎患者抑郁发病情况的文献。由2名研究者独立筛选文献建立数据库,使用R4。2。2软件进行Meta分析。结果 共纳入40篇文献,8535例类风湿关节炎患者中4075例检出抑郁症状,中国类风湿关节炎患者抑郁发病率44。70%(95%CI:38。90~50。44);亚组分析结果显示女性患者抑郁发病率[28。52%(95%CI:20。22~38。58)]高于男性[6。78%(95%CI:4。92~9。27)],差异有统计学意义(P=0。0002);不同评估工具测得抑郁发生率存在统计学差异(P<0。0001)。结论 我国类风湿关节炎患者抑郁发病率较高,需要关注患者心理状态,并采取干预措施以提供有效支持。
Meta-analysis of the Incidence of Depression in Patients with Rheumatoid Arthritis in China
Objective To understand the incidence of depression in patients with rheumatoid arthritis in China,and to provide reference for clinical practice.Methods The literature on the incidence of depression in patients with rheumatoid arthritis in China published from the establishment of the database to February 2023 was searched in China Knowledge Network Infrastructure,Wanfang,VIP,SinoMed,PubMed and MedlineComplete databases.Two researchers independently screened literature to establish a database,and meta-analysis was performed using R4.2.2 software.Results A total of 40 literatures were included,and 4075 of 8535 patients with rheumatoid arthritis were found to have depressive symptoms.The incidence of depression in Chinese patients with rheumatoid arthritis was 44.70%(95%CI:38.90-50.44).The results of subgroup analysis showed that the incidence of depression in female patients[28.52%(95%CI:20.22-38.58)]was higher than that in male patients[6.78%(95%CI:4.92-9.27)],and the difference was statistically significant(P=0.0002).There was a statistically significant difference in the incidence of depression measured by different assessment tools(P<0.0001).Conclusion The incidence of depression in patients with rheumatoid arthritis in China is high.It is necessary to pay attention to the psychological state of patients and take intervention measures to provide effective support.

Rheumatoid arthritisDepressionPrevalence

徐美丽、王文怡、施雨燕、彭雄、刘梨

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湖南中医药大学第一附属医院风湿免疫科,湖南 长沙 410007

湖南中医药大学护理学院,湖南 长沙 410208

类风湿关节炎 抑郁 患病率

国家自然科学基金项目湖南省中医药管理局基金项目

82274627A2023010

2024

医学信息
国家卫生部信息化管理领导小组 中国电子学会中国医药信息学分会 陕西文博生物信息工程研究所

医学信息

影响因子:0.161
ISSN:1006-1959
年,卷(期):2024.37(3)
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