Comparative of Serum Pepsinogen in Hui and Han Nationalities Patients with Gastric Cancer and Gastric Ulcer in Jingzhou Area
Objective To study the significance of serum pepsinogen(PG)Ⅰ,PG Ⅱ and PGR values in patients with gastric cancer(GC)and gastric ulcer(GU)in Han and Hui nationalities in Jingzhou area,and to explore the differences between Han and Hui nationalities.Methods A total of 118 patients with GC and GU diagnosed for the first time in the Second Hospital of Jingzhou from January 2016 to June 2021 were selected and grouped according to the disease and nationality,including 30 patients as Han nationality GC group,28 patients as Hui nationality GC group,and 30 patients as Hui nationality and Han nationality GU group.The levels of PG Ⅰ,PG Ⅱ and PGR in each group were compared.Results The levels of serum PGⅠ and PGR in Han nationality GC group and Hui nationality GC group were lower than those in the same ethnic GU group,and the level of serum PG Ⅱ was higher than that in the same ethnic GU group,the differences were statistically significant(P＜0.05).The level of serum PG Ⅰ in the Han nationality GC group was higher than that in the Hui nationality GC group,the level of serum PG Ⅱ was lower than that in the Hui nationality GC group,and the difference was not statistically significant(P＞0.05).The level of PGR in Han nationality GC group was lower than that in the Hui nationality GC group,the difference was statistically significant(P＜0.05).The levels of serum PG Ⅰ and PGR in Han nationality GC group were higher than those in the Hui nationality GC group,and the level of serum PG Ⅱ was lower than that in the Hui nationality GC group,but the difference was not statistically significant(P＞0.05).Conclusion Compared with GU patients,the levels of serum PG Ⅰ and PGR in GC patients decrease and PG Ⅱ increases,which has certain clinical significance for the screening of GC in this region.In addition,the PGR level of Han GU patients is lower than that of Hui GC patients,while there is no difference in PG level between Han and Hui nationality GU patients.
万方数据
维普
