Research Status of the Role of Inflammatory Factors in AIDS Complicated with Lymphoma
AIDS-related lymphoma(ARL)is one of the most common malignant tumors in HIV/AIDS patients.IL-6 is a cytokine with pleiotropic immunomodulatory activity,which is closely related to the occurrence,development,invasion,metastasis and prognosis of tumors.CRP is a sensitive inflammatory marker,which can be increased in the early stage of infection,and is synthesized in hepatocytes,mainly due to the induction of cytokines such as IL-6 and TNF-α after infection.PCT can be used as a biomarker of systemic inflammatory response,which is commonly used to identify bacterial infections and other inflammatory infections.D-dimer(D-D)is a sensitive indicator of fibrin formation and degradation.Factors such as surgery,malignant tumors and renal insufficiency can lead to an increase in D-dimer.This article reviews the effects of IL-6,CRP,PCT and D-D on tumors,especially lymphoma,in order to provide a reference for exploring the role of the above inflammatory factors in AIDS complicated with lymphoma.
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维普
