Analysis of Clinical Characteristics of Diarrhea Caused by Piperacillin/Tazobactam
Objective To summarize the clinical characteristics of diarrhea caused by piperacillin/tazobactam,and to provide reference for rapid and accurate judgment of adverse drug reactions in clinical medication,so as to ensure safe and effective medication.Methods A total of 26 cases of diarrhea caused by piperacillin/tazobactam admitted to Guigang City People's Hospital from January 2014 to December 2022 were collected.The gender,age distribution,clinical manifestations,medication time,cumulative dose,laboratory examination results,clinical treatment methods and outcomes were statistically analyzed.Results After medication(<36 g or less),most patients showed stool frequency increased and watery stools in two days,but improved after they stopped drugs and symptomatic treatment.Conclusion Clinically,perfect inspection to assess patient's condition,stopping medication timely or adjusting treatment plan are helpful to improve with piperacillin/tazobactam related diarrhea.