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甲型和乙型流感阳性儿童临床特征分析

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目的 分析甲型和乙型流感阳性儿童的临床特征.方法 选取2020年1月-2022年5月我院诊治的70例流感儿童为研究对象,其中甲型流感患儿36例,乙型流感患儿34例,比较两组C反应蛋白(CRP)、白细胞(WBC)、中性粒细胞(NEU)绝对值、血小板、白介素(IL)-6、CRP水平,以及CRP、WBC、NEU占比情况,临床症状(恶心呕吐、腹泻、流涕、咽痛、肌肉酸痛、咳嗽、喘息)发生率、T淋巴细胞(CD3+、CD4+、CD8+)水平和并发症(病毒性肺炎、抽搐)发生情况.结果 甲型流感阳性患儿血小板计数、IL-6水平均高于乙型流感阳性患儿(P<0.05),而两组CRP、WBC水平及NEU绝对值比较,差异无统计学意义(P>0.05).甲型流感阳性患儿CRP>5 mg/L、NEU>7.0×109/L、WBC>10×109/L占比低于乙型流感阳性患儿(P<0.05).甲型流感阳性患儿恶心呕吐、腹泻、流涕发生率均低于乙型流感阳性患儿(P<0.05),而两组咽痛、肌肉酸痛、咳嗽、喘息发生率比较,差异无统计学意义(P>0.05).甲型流感阳性患儿CD3+、CD4+、CD8+均低于乙型流感阳性患儿(P<0.05).甲型流感阳性患儿病毒性肺炎、抽搐发生率均高于乙型流感阳性患儿(P<0.05).结论 甲型和乙型流感阳性儿童患者临床特征存在差异,可通过对比血小板计数、IL-6、临床症状、合并症以及免疫功能指标进行鉴别判断,从而为临床治疗提供依据.
Analysis of Clinical Characteristics of Children with Influenza A and Influenza B Viruses
Objective To analyze the clinical characteristics of children with influenza A and influenza B viruses.Methods A total of 70 children with influenza diagnosed and treated in our hospital from January 2020 to May 2022 were selected as the research objects,including 36 children with influenza A viruses and 34 children with influenza B viruses.The levels of C-reactive protein(CRP),white blood cell(WBC),absolute value of neutrophil(NEU),platelet,interleukin(IL)-6,CRP,and the proportion of CRP,WBC and NEU were compared between the two groups.Meanwhile,the incidence of clinical symptoms(nausea and vomiting,diarrhea,runny nose,sore throat,muscle soreness,cough,wheezing),T lymphocyte(CD3+,CD4+,CD8+)levels and complications(viral pneumonia,convulsions)were compared between the two groups.Results The levels of platelet count and IL-6 in children with influenza A viruses were higher than those in children with influenza B viruses(P<0.05),there was no significant difference in CRP,WBC and NEU levels between the two groups(P>0.05).The proportion of CRP>5 mg/L,NEU>7.0×109/L and WBC>10×109/L in children with influenza A viruses was lower than that in children with influenza B viruses(P<0.05).The incidence of nausea,vomiting,diarrhea and runny nose in children with influenza A viruses was lower than that in children with influenza B viruses(P<0.05),while there was no significant difference in the incidence of sore throat,muscle pain,cough and wheezing between the two groups(P>0.05).The CD3+,CD4+and CD8+of children with influenza A viruses were lower than those of children with influenza B viruses(P<0.05).The incidence of viral pneumonia and convulsions in children with influenza A viruses was higher than that in children with influenza B viruses(P<0.05).Conclusion There are differences in clinical characteristics between children with influenza A and influenza B viruses.Platelet count,IL-6,clinical symptoms,complications and immune function indexes can be compared to identify and judge,so as to provide basis for clinical treatment.

Influenza AInfluenza BC-reactive proteinWhite blood cells

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金溪县人民医院检验科,江西 金溪 344800

甲型流感 乙型流感 C反应蛋白 白细胞

2024

医学信息
国家卫生部信息化管理领导小组 中国电子学会中国医药信息学分会 陕西文博生物信息工程研究所

医学信息

影响因子:0.161
ISSN:1006-1959
年,卷(期):2024.37(4)
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