Effect of Pterygium Excision Combined with Autologous Limbal Stem Cell Transplantation on Visual Acuity and Prognosis in Patients with Pterygium
Objective To investigate the effect of pterygium excision combined with autologous limbal stem cell transplantation(CAT)on visual acuity and prognosis in patients with pterygium.Methods A total of 60 patients with pterygium admitted to Tianjin Jizhou District People's Hospital from November 2018 to November 2022 were selected as the research objects and divided into control group(30 patients)and observation group(30 patients)by random number table method.The control group was treated with pterygium excision,and the observation group was treated with CAT on the basis of the control group.The visual acuity,corneal astigmatism,postoperative recovery(corneal epithelial repair time,wound healing time,suture removal time),complications and prognosis were compared between the two groups.Results At 3 days after operation,the visual acuity of the observation group was higher than that before operation(P＜0.05).At 1-2 weeks after operation,the visual acuity of the two groups was higher than that before operation,and that of the observation group was higher than that of the control group(P＜0.05).At 1 month and 3 months after operation,the corneal astigmatism of the two groups was lower than that before operation,and the corneal astigmatism of the observation group was lower than that of the control group(P＜0.05).The corneal epithelial repair time,wound healing time and suture removal time in the observation group were shorter than those in the control group(P＜0.05).The incidence of complications in the observation group was lower than that in the control group(P＜0.05).There was significant difference in prognosis between the two groups(P＜0.05).Conclusion Pterygium resection combined with CAT is effective in the treatment of pterygium,which can effectively improve the visual acuity of patients and improve their astigmatism.Meanwhile,it has the advantages of rapid postoperative recovery and low risk of complications,and has a good improvement effect on the prognosis of the disease.
万方数据
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