Effect of Carboprost Tromethamine Combined with Oxytocin on Prevention and Treatment of Postpartum Hemorrhage Caused by Placenta Previa
Objective To study the effect of carboprost tromethamine combined with oxytocin in the prevention and treatment of postpartum hemorrhage caused by placenta previa.Methods A total of 64 pregnant women with placenta previa who were diagnosed and treated in our hospital from May 2021 to May 2022 were selected as the research objects.They were divided into control group and observation group by random number table method,with 32 pregnant women in each group.The control group was treated with oxytocin,and the observation group was treated with carboprost tromethamine on the basis of the control group.The incidence of postpartum hemorrhage,bleeding volume at different time periods,coagulation function indexes,adverse reactions and complications were compared between the two groups.Results The incidence of postpartum hemorrhage in the observation group(15.63％)was lower than that in the control group(25.00％)(P＜0.05).The amount of bleeding during delivery,2 h and 24 h after delivery in the observation group was less than that in the control group(P＜0.05).The levels of prothrombin time(PT)and activated partial thromboplastin time(APTT)in the observation group were lower than those in the control group,and fibrinogen(FIB)was higher than that in the control group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the observation group and the control group(P＞0.05).The incidence of complications in the observation group was 9.38％,which was lower than 21.88％in the control group(P＜0.05).Conclusion The combination of carboprost tromethamine and oxytocin can effectively reduce the incidence of within 24 hours and improve the coagulation function without significant adverse reactions,it is worthy of clinical application.
万方数据
维普
