Analysis of Pathogenic Culture Results and Drug Resistance of Community-acquired Pneumonia in a Hospital in Baise City,Guangxi from 2021 to 2022
Objective To analyze the pathogenic culture results and drug resistance of community-acquired pneumonia cases,so as to provide evidence for rational use of antibiotics and avoidance of drug resistance.Methods The clinical data,pathogen culture results and drug resistance data of 130 cases of community-acquired pneumonia in Baise Maternal and Child Health Hospital from 2021 to 2022 were collected and analyzed.Results A total of 60 strains of pathogenic bacteria were detected in the sputum culture results of 130 patients with community-acquired pneumonia(46.15%),including 34 strains of gram-negative bacteria(56.67%),mainly Klebsiella pneumoniae;there were 23 strains of gram-positive bacteria(38.33%),mainly Streptococcus pneumoniae;there were 3 strains of fungi(5.00%),which were all Candida.Gram-positive bacteria and negative bacteria were sensitive to vancomycin and imipenem.Gram-positive bacteria were relatively sensitive to quinolones and cephalosporin antibiotics,and partially resistant to penicillin,ampicillin and clindamycin.Gram-negative bacteria are partially resistant to drugs such as gentamicin.Conclusion The pathogenic bacteria of community-acquired pneumonia in the jurisdiction are mainly gram-negative bacteria,followed by gram-positive bacteria;the results of drug sensitivity culture show that all of them are sensitive to vancomycin and imipenem,most of them are sensitive to amoxicillin,levofloxacin and ceftriaxone,and most of them are resistant to penicillin,gentamicin and cefuroxime.It is recommended that clinicians should rationally use antibiotics in the treatment of community-acquired pneumonia and dynamically monitor the drug resistance of pathogens.