Predictive Value of Plasma cTn-T,ME and NT-proBNP Levels in Major Adverse Cardiovascular Events for Patients with Acute Chest Pain
Objective To explore the predictive value of plasma troponin(cTn-T),methoxyestradiol(ME)and N-terminal pro-brain natriuretic peptide(NT-proBNP)levels in major adverse cardiovascular events(MACE)for patients with acute chest pain.Methods A total of 96 patients with acute chest pain admitted to the emergency department of Dujiangyan Maternal and Child Health Hospital from July 2021 to July 2022 were selected as the chest pain group,and 90 healthy people who underwent physical examination during the same period were selected as the control group.According to the occurrence of MACE,the patients in the chest pain group were divided into MACE group and non-MACE group.The levels of plasma cTn-T,ME and NT-proBNP were compared between the chest pain group and the control group,the MACE group and the non-MACE group.The risk factors affecting the occurrence of MACE in patients with acute chest pain and the value of plasma cTn-T,ME and NT-proBNP levels in predicting the occurrence of MACE in patients with acute chest pain were analyzed.Results The levels of plasma cTn-T and NT-proBNP in the chest pain group were higher than those in the control group,and the level of plasma ME was lower than that in the control group(P＜0.05).In the chest pain group,there were 3 cases of emergency revascularization,4 cases of stroke,5 cases of myocardial infarction,3 cases of cardiogenic shock,3 cases of ventricular fibrillation/ventricular arrest and 1 case of all-cause death 90 days after discharge,the incidence of MACE was 19.79％(19/96).The levels of plasma cTn-T and NT-proBNP in MACE group were higher than those in non-MACE group,and the level of plasma ME was lower than that in non-MACE group(P＜0.05).Multivariate Logistic regression analysis showed that the increase of cTn-T level,the decrease of ME level and the increase of NT-proBNP level were independent risk factors for MACE in patients with acute chest pain.ROC curve analysis showed that the AUC values of plasma cTn-T,ME and NT-proBNP levels for predicting MACE in patients with acute chest pain were 0.923,0.695 and 0.803,respectively.Conclusion The levels of plasma cTn-T,ME and NT-proBNP in patients with acute chest pain are abnormal,which can effectively predict the risk of MACE.
万方数据
维普
