首页|免疫胶体金法应用于人腺病毒抗原检测的区域结果分析

免疫胶体金法应用于人腺病毒抗原检测的区域结果分析

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目的 分析腺病毒抗原阳性患者在建德市的流行病学特点.方法 采集2021年9月-2023年8月来建德市第一人民医院40 646例发热患者的鼻咽部拭子标本,用免疫胶体金法对患者的鼻咽部拭子标本进行腺病毒抗原检测,并对阳性结果进行回顾性分析.结果 2021年9月-2023年8月腺病毒抗原检测结果阳性患者596例,占总发热人数比例为1.47%.其中2021年9月-2022年8月腺病毒抗原检测结果阳性患者377例,在本年发热患者中所占比例为2.24%;2022年9月-2023年8月阳性患者219例,占本年发热患者比例为0.84%;总体的阳性率呈现降低趋势.以年龄为分组进行分析发现,年龄≤12岁的腺病毒感染阳性率高于年龄>12岁的腺病毒感染阳性率,差异有统计学意义(P<0.05).以季节为分组分析发现,春夏季节的腺病毒感染阳性率高于秋冬季的腺病毒感染阳性率,差异有统计学意义(P<0.05).结论 近两年来建德市人腺病毒抗原检测阳性患者在发热患者中所占比例呈现降低趋势,建德市人腺病毒感染与年龄分布和季节更替有关.
Analysis of Regional Results of Human Adenovirus Antigen Detection by Immunocolloidal Gold Method
Objective To analyze the epidemiological characteristics of adenovirus antigen positive patients in Jiande City.Methods Nasopharyngeal swab specimens of 40 646 patients with fever in the First People's Hospital of Jiande City from September 2021 to August 2023 were collected.Adenovirus antigen was detected in nasopharyngeal swab specimens of patients by immunocolloidal gold method,and the positive results were retrospectively analyzed.Results From September 2021 to August 2023,there were 596 patients with positive adenovirus antigen test results,accounting for 1.47%of the total number of fever patients.Among them,377 patients with positive adenovirus antigen test results from September 2021 to August 2022,accounting for 2.24%of the patients with fever in this year.From September 2022 to August 2023,there were 219 positive patients,accounting for 0.84%of the patients with fever in this year;the overall positive rate showed a decreasing trend.The positive rate of adenovirus infection under 12 years old(including 12 years old)was higher than that of adenovirus infection over 12 years old,and the difference was statistically significant(P<0.05).The positive rate of adenovirus infection in spring and summer was higher than that in autumn and winter,and the difference was statistically significant(P<0.05).Conclusion In the past two years,the proportion of patients with positive human adenovirus antigen detection in patients with fever in Jiande City has shown a decreasing trend.Human adenovirus infection in Jiande City is related to age distribution and seasonal change.

FeverAdenovirus infectionEpidemiologyAntigen detectionImmunocolloidal gold method

朱逢龙、赵西耀

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建德市第一人民医院检验科,浙江建德 311600

发热 腺病毒感染 流行病学 抗原检测 免疫胶体金法

杭州市科技计划引导项目(2020)

20201231Y176

2024

医学信息
国家卫生部信息化管理领导小组 中国电子学会中国医药信息学分会 陕西文博生物信息工程研究所

医学信息

影响因子:0.161
ISSN:1006-1959
年,卷(期):2024.37(7)
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