Research Progress of Signaling Pathways on Regulating Dentinogenesis
Dentin is an important hard tissue of the tooth.Dentinogenesis is strictly under genetic regulation.Mastering this huge network of regulation system is beneficial to elucidate the molecular mechanism of dentin development,regeneration and repair,and further develop novel research ideas and treatment methods for dentin related diseases,which will help to solve some dental diseases.Aiming at the growth factors,transcription factors and other signaling molecules that regulate dentin formation,this review systematically summarizes the signaling pathways and genes that regulate dentin development and provides theoretical and experimental references for dentin development research and disease treatment.