Hypoparathyroidism(HPT)is usually caused by surgical injuries of thyroid,throat and other head-neck tumors,and it is also a urgent problem in the field of thyroid surgery.Strengthening perioperative management is the key to prevent postoperative hypoparathyroidism.As a traditional treatment,long-term supplementation of calcium and vitamin D may induce complications such as ectopic calcification and decreased renal function,which may lead to loss of working ability in some patients and affect the quality of life and long-term prognosis.In recent years,recombinant human parathyroid polypeptide replacement,parathyroid allotransplantation and stem cell cotransplantation technology may become very promising therapeutic strategies.This article summarizes the causes and inducing factors of HPT after thyroid surgery,and reviews the possible effective prevention methods and treatment strategies found in recent years,aiming to provide new ideas for clinical prevention and treatment of HPT.
关键词
甲状腺切除术/甲状旁腺功能减退/围手术期预防/重组人甲状旁腺激素/甲状旁腺移植
Key words
Thyroidectomy/Hypoparathyroidism/Perioperative management/Recombinant human parathyroid hormone/Parathyroid transplantation