Value of Combined Detection of Fibrinogen,D-dimer and Ferritin in the Diagnosis of Upper Respiratory Tract Infection in Children
Objective To investigate the diagnostic value of fibrinogen(FIB),D-dimer(D-D)and serum ferritin(FER)in children with upper respiratory tract infection.Methods A total of 96 children with upper respiratory tract infection diagnosed in Huangshi Municipal Maternal and Child Health Care Hospital from December 2022 to February 2023 were collected as observation group.According to the results of etiological diagnosis,they were divided into viral infection group(n=55)and bacterial infection group(n=41).In addition,96 children with normal results who underwent routine physical examination in our hospital during the same period were selected as the control group.The differences of FIB,D-D and FER levels in each group were compared.Logistic multiple regression model was used to analyze the influencing factors of upper respiratory tract infection in children.ROC curve was used to analyze the value of combined detection of FIB,D-D and FER in the diagnosis of upper respiratory tract infection in children.Results The levels of FIB,D-D and FER in the observation group were higher than those in the control group(P＜0.05),and the levels of FIB,D-D and FER in the bacterial infection group were higher than those in the viral infection group(P＜0.05).Logistic multiple regression model analysis showed that FIB,D-D and FER levels were independent risk factors for upper respiratory tract infection in children(P＜0.05).ROC curve analysis showed that the area under the ROC curve of FIB,D-D and FER combined detection was 0.966(95％CI:0.944-0.989),and the sensitivity and specificity were 89.65％and 96.93％,respectively,which were higher than those of the three alone.Conclusion Routine combined detection of FIB,D-D and FER levels is helpful to provide some reference for clinical diagnosis of upper respiratory tract infection in children.
万方数据
维普
