Effect of Long-term Autologous Arteriovenous Fistula Maintenance Hemodialysis on Cardiac Structure in Patients with Chronic Kidney Disease
Objective To study the effect of long-term autologous arteriovenous fistula maintenance hemodialysis on cardiac structure in patients with chronic kidney disease.Methods A total of 80 patients with chronic kidney disease who underwent long-term autologous arteriovenous fistula maintenance hemodialysis in our hospital from February 2021 to February 2023 were selected as the research objects.According to the dialysis age,they were divided into＜5 years(36 patients),5-10 years(30 patients),≥10 years(14 patients).The renal function indexes(urea nitrogen,creatinine,β2 microglobulin),incidence of cardiovascular complications and cardiac structure indexes of patients with different dialysis ages were observed.Results The levels of urea nitrogen,creatinine and β2 microglobulin in patients with dialysis age＜5 years were lower than those in patients with dialysis age of 5-10 years and≥10 years(P＜0.05),but there was no significant difference in the levels of urea nitrogen and β2 microglobulin between patients with dialysis age of 5-10 years and ≥10 years(P＞0.05).The creatinine level of patients with dialysis age ≥10 years was higher than that of patients with dialysis age of 5-10 years(P＜0.05).The incidence of hypertension in patients with dialysis age＜5 years and 5-10 years was higher than that in patients with dialysis age ≥ 10 years(P＜0.05).There was no significant difference in the incidence of hypertension between patients with dialysis age＜5 years and 5-10 years(P＞0.05).There was no significant difference in the incidence of acute left heart failure,myocardial infarction,coronary heart disease and cardiac insufficiency among patients with different dialysis ages(P＞0.05).The proportion of normal cardiac structure in patients with dialysis age＜5 years was lower than that in patients with dialysis age＜5 years and 5-10 years(P＜0.05),but there was no significant difference in the proportion of normal cardiac structure between patients with dialysis age＜5 years and 5-10 years(P＞0.05).There was no significant difference in the proportion of left atrial enlargement,left ventricular hypertrophy,ventricular septal thickening,whole heart enlargement and left ventricular ejection fraction reduction in patients with different dialysis ages(P＞0.05).Conclusion Long-term autologous arteriovenous fistula maintenance hemodialysis in the treatment of chronic kidney disease can maintain the basic stability of cardiac structure.At the same time,with the prolongation of dialysis time,the condition will fluctuate.Although the renal function indexes urea nitrogen and creatinine will change,the incidence of hypertension will decrease.The patient's heart has a strong ability to adapt and compensate for hypertension and volume load,which is conducive to the improvement of the condition.
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