摘要
原发性闭角型青光眼(PACG)是临床上常见的极易威胁视力的青光眼类型,其发病因素复杂,包括短眼轴、浅前房、窄房角、晶状体等局部解剖因素及性别、年龄、家族史等其它因素.近年来,随着眼科影像学技术的发展,已经可以通过超声生物显微镜(UBM)、眼前节相干光断层扫描成像技术(AS-OCT)等检查清晰地观察到眼内的解剖结构,进而研究其在房角关闭机制中的作用.研究者们对于PACG影响因素的探究也趋于细化、量化.本文主要对近年来晶状体因素在PACG发病机制中的作用进行综述,旨在为临床工作中PACG的早期诊断和干预提供指导作用.
Abstract
Primary angle-closure glaucoma(PACG)is a common type of glaucoma that is extremely threatening to vision in clinical practice.Its pathogenic factors are complex,including local anatomical factors such as short axis,shallow anterior chamber,narrow chamber angle,lens and other factors such as gender,age,family history and so on.In recent years,with the development of ophthalmic imaging technology,the anatomical structure of the eye can be clearly observed by ultrasound biomicroscopy(UBM),anterior segment optical coherence tomography(AS-OCT)and other examinations,and then its role in the mechanism of angle closure can be studied.The researchers'exploration of the influencing factors of PACG also tends to be refined and quantified.This article reviews the role of lens factors in the pathogenesis of PACG in recent years,aiming to provide guidance for early diagnosis and intervention of PACG in clinical work.