摘要
目的 总结严光俊教授治疗胃癌的用药规律.方法 收集严光俊教授治疗胃癌医案120例,符合纳入标准的病案资料录入"古今医案云平台(V2.3.5版本)",运用"数据挖掘"模块中的统计分析、关联分析等分析方法,总结严光俊教授治疗胃癌的用药特色、应用规律和经验.结果 120例医案用药共164种,以补气、健脾、祛湿、化痰、清热解毒、滋阴、温阳、行气、活血化瘀类药物为主.治法按频率排序依次为:补气通痞化积法＞扶阳通痞化积法＞清热通痞化积法＞养阴通痞化积法＞祛痰通痞化积法＞活血通痞化积法＞解毒通痞化积法.对排序前3的治法进行药物关联分析,置信度设为0.9,支持度设为0.5,补气通痞化积法得到关联规则药物7条,扶阳通痞化积法关联规则药物19条,清热通痞化积法关联药物16条.结论 严光俊教授治疗胃癌的治疗以养脾胃、扶正固本,注重通降、调气机,抗癌解毒贯穿始终为治疗原则,为胃癌临床用药提供指导.
Abstract
Objective To summarize the medication rules of Professor YAN Guang-jun in the treatment of gastric cancer.Methods The medical records of 120 cases of gastric cancer treated by Professor YAN Guang-jun were collected,and the medical records that met the inclusion criteria were entered into the"Ancient and Modern Medical Records Cloud Platform(Version 2.3.5)".The statistical analysis,correlation analysis and other analysis methods in the data mining module were used to summarize the medication characteristics,application rules and experience of Professor YAN Guang-jun in the treatment of gastric cancer.Results A total of 164 kinds of drugs were used in 120 medical cases,mainly for tonifying qi,invigorating spleen,dispelling dampness,resolving phlegm,clearing heat and detoxifying,nourishing yin,warming yang,promoting qi,promoting blood circulation and removing blood stasis.The order of treatment according to frequency was:Buqi Tongpi Huaji method＞Fuyang Tongpi Huaji method＞Qingre Tongpi Huaji method＞Yangyin Tongpi Huaji method＞Qutan Tongpi Huaji method＞Huoxue Tongpi Huaji method＞Jiedu Tongpi Huaji method.The drug association analysis was performed on the top 3 treatment methods,the confidence level was set to 0.9,and the support level was set to 0.5,there were 7 association rule drugs were obtained by Buqi Tongpi Huaji method,19 association rule drugs were obtained by Fuyang Tongpi Huaji method,and 16 association drugs were obtained by Qingre Tongpi Huaji method.Conclusion Professor YAN Guang-jun in the treatment of gastric cancer is based on the principle of nourishing the spleen and stomach,strengthening the body,paying attention to the descending and regulating qi,and anti-cancer and detoxification throughout the treatment,so as to provide guidance for clinical medication of gastric cancer.
维普
万方数据