Effect of Gestational Weight Gain on Pregnancy Outcome and Neonatal Outcome in Obese Patients with Gestational Diabetes Mellitus
Objective To compare the effects of different degrees of gestational weight gain(GWG)on maternal and neonatal outcomes.Methods The clinical data of 324 obese pregnant women with gestational diabetes mellitus who gave birth in the obstetrics department of Anqing Hospital,Anhui Medical University from December 2020 to December 2022 were collected.According to the weight gain during pregnancy,they were divided into GWG insufficient group(n=110),GWG appropriate group(n=108)and GWG excessive group(n=106).The pregnancy outcomes and neonatal outcomes of the three groups were compared.Results Compared with the GWG appropriate group and the GWG excessive group,the proportion of gestational hypertension,the proportion of preeclampsia,the incidence of cesarean section and the level of HbA1c in the third trimester were lower in the GWG insufficient group,BMI and the proportion of postpartum blood glucose returning to normal was higher,the difference was statistically significant(P<0.05).The neonatal birth weight and the incidence of macrosomia and LGA in the GWG insufficient group were lower than those in the GWG appropriate and GWG excessive groups(P<0.05).Logistic multivariate regression analysis showed that the risk of LGA,preeclampsia,cesarean section and diabetes in the GWG insufficient group was significantly reduced;the risk of LGA and cesarean section was significantly increased in the GWG excessive group.Conclusion GDM obese women with excessive weight gain during pregnancy have a higher incidence of adverse outcomes,and insufficient weight gain is more conducive to good pregnancy outcomes and neonatal outcomes.