Research Progress on Factors and Mechanism of Adjacent Segment Degeneration After Lumbar Fusion
Degenerative diseases of the lumbar spine often cause chronic low back pain.Lumbar decompression and fusion surgery is the main and effective method for the treatment of degenerative diseases of the lumbar spine,and has achieved remarkable clinical results.However,long-term follow-up found that the incidence of adjacent segment lesions after lumbar fusion was not low,which was the main factor leading to secondary surgery.The mechanism of adjacent segment degeneration after lumbar fusion involves many disciplines and factors such as biomechanics,physiopathology,molecular biology,etc.It is a complex physiological and pathological development process.This article reviews the factors and mechanisms of adjacent segment lesions after lumbar fusion,in order to provide a theoretical reference for clinical surgery to formulate surgical plans and provide a theoretical basis for the intervention of adjacent segment lesions.