医学信息2024,Vol.37Issue(10) :175-178.DOI:10.3969/j.issn.1006-1959.2024.10.038

肠道屏障在非酒精性脂肪性肝病发生发展中的作用

Role of Intestinal Barrier in the Development of Nonalcoholic Fatty Liver Disease

高书娟 戴光荣
医学信息2024,Vol.37Issue(10) :175-178.DOI:10.3969/j.issn.1006-1959.2024.10.038

肠道屏障在非酒精性脂肪性肝病发生发展中的作用

Role of Intestinal Barrier in the Development of Nonalcoholic Fatty Liver Disease

高书娟 1戴光荣1
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作者信息

  • 1. 延安大学附属医院消化内科,陕西延安 716000
  • 折叠

摘要

非酒精性脂肪性肝病(NAFLD)在我国的发病率逐年上升.肠道屏障是肠道能防止肠腔内的有害物质如细菌和内毒素等穿过肠黏膜进入体内其他组织器官和血液循环的结构和功能的总和,通常将肠道屏障分为肠道机械屏障、肠道免疫屏障、肠道化学屏障、肠道微生物屏障.本文对肠道黏膜屏障功能在NAFLD发病机制中的重要作用,以及肠道屏障功能的研究进行总结,探讨NAFLD的预防和治疗.

Abstract

The incidence of nonalcoholic fatty liver disease(NAFLD)in China is increasing year by year.Intestinal barrier refers to the sum of the structure and function of the intestine to prevent harmful substances such as bacteria and endotoxin in the intestinal cavity from passing through the intestinal mucosa into other tissues and organs in the body and blood circulation.Intestinal barrier is usually divided into intestinal mechanical barrier,intestinal immune barrier,intestinal chemical barrier and intestinal microbial barrier.This article summarizes the important role of intestinal mucosal barrier function in the pathogenesis of NAFLD and the study of intestinal barrier function,and discusses the prevention and treatment of NAFLD.

关键词

非酒精性脂肪性肝病/肠道屏障/黏膜屏障

Key words

Non-alcoholic fatty liver disease/Intestinal barrier/Mucosal barrier

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基金项目

延安大学附属医院科学技术研究发展计划(2022ZD-07)

出版年

2024
医学信息
国家卫生部信息化管理领导小组 中国电子学会中国医药信息学分会 陕西文博生物信息工程研究所

医学信息

影响因子:0.161
ISSN:1006-1959
参考文献量31
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