Role of Intestinal Barrier in the Development of Nonalcoholic Fatty Liver Disease
The incidence of nonalcoholic fatty liver disease(NAFLD)in China is increasing year by year.Intestinal barrier refers to the sum of the structure and function of the intestine to prevent harmful substances such as bacteria and endotoxin in the intestinal cavity from passing through the intestinal mucosa into other tissues and organs in the body and blood circulation.Intestinal barrier is usually divided into intestinal mechanical barrier,intestinal immune barrier,intestinal chemical barrier and intestinal microbial barrier.This article summarizes the important role of intestinal mucosal barrier function in the pathogenesis of NAFLD and the study of intestinal barrier function,and discusses the prevention and treatment of NAFLD.