Analysis of the Characteristics and Drug Resistance of Clinically Detected Pathogens in Malipo County People's Hospital from 2020 to 2021
Objective To investigate the composition characteristics and drug resistance of pathogenic bacteria detected in Malipo County People's Hospital of Yunnan Province,and to provide basis for clinical rational application of antibiotics.Methods The clinical isolates of pathogenic bacteria were collected from January 2020 to December 2021 in Malipo County People's Hospital of Yunnan Province.The bacterial identification and the minimum inhibitory concentration(MIC)of antibiotics were detected by Xinke XK bacterial identification/drug sensitivity analyzer.The results were analyzed by WHONET 5.6 software.Results A total of 892 strains of pathogenic bacteria were detected from 2020 to 2021.The main sources of specimens were pus(51.79％),blood culture(16.59％)and midstream urine specimens(16.59％).Among the pathogenic bacteria detected,hospitalization accounted for 93.39％,and outpatient and emergency departments accounted for 6.61％.The number of strains detected in outpatient and emergency departments in 2021 was more than that in 2020,and the difference was statistically significant(P＜0.05).438 strains of Gram-negative bacteria,414 strains of Gram-positive bacteria and 40 strains of fungi were detected.Escherichia coli(204 strains,35.85％)and Staphylococcus aureus(147 strains,25.83％)were the most common pathogens.Escherichia coli and Klebsiella pneumoniae were highly resistant to cefazolin and ampicillin/sulbactum,and the resistance rates were more than 50.00％.The resistance rates of Pseudomonas aeruginosa and Acinetobacter baumannii to imipenem were 36.36％and 54.05％,respectively.The detection rate of MRSA in Staphylococcus aureus was 53.06％,and the detection rate of MRCNS in coagulase negative Staphylococcus was 54.61％.No vancomycin-resistant strains were found in either Staphylococcus aureus or coagulase-negative Staphylococcus.Conclusion The detection rate of drug-resistant bacteria in Malipo County People's Hospital of Yunnan Province is high.The clinical determination of drug resistance should be strengthened to promote rational drug use and reduce the incidence of hospital infection.
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