Research Progress on the Etiology of Modic Low Back Pain
Low back pain is a clinical symptom caused by one or more known or unknown diseases.With the increasing population and aging of the world,the incidence of low back pain is increasing year by year.Vertebral Modic changes(MCs)are visual signals of changes in the vertebral bone marrow in magnetic resonance imaging(MRI).With the deepening of research,it has been found that these different MCs represent different pathological changes.At present,a large number of studies have shown that Modic type Ⅰ changes are closely related to low back pain.The etiology of Modic low back pain is not clear,but it is closely related to intervertebral disc degeneration,endplate injury,infection,immune response and other factors.This article reviews the research progress of etiology of Modic low back pain at home and abroad in recent years,in order to provide guidance for clinical treatment of Modic low back pain.
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