Research Status of Levosimendan in Cardiac Surgery
Levosimendan is a new generation of positive inotropic drug that has great potential for use in cardiac surgery,as it avoids the risk of increased myocardial oxygen consumption associated with traditional cardiac drugs.Only some clinical studies have confirmed the benefits of levosimendan in cardiac surgery in terms of hemodynamics,blood test indexes,and hospital stay,while its advantages in terms of heart failure incidence and mortality have not surpassed those of traditional positive inotropic drugs.This article reviews the mechanism of action of levosimendan and its use in different time periods in the perioperative period of cardiac surgery to provide a reference for its clinical application.