Pharmaceutical Care Effect of Clinical Pharmacists Participating in Individualized Administration of Anti-infective Drugs in Patients with Renal Failure
Objective To study the pharmaceutical care effect of clinical pharmacists participating in individualized administration of anti-infective drugs in patients with renal failure.Methods A total of 80 patients with renal failure who were admitted to our hospital from January 2022 to January 2023 were selected as the research objects.They were divided into observation group(n=40)and control group(n=40)by random number table method.The control group was given medical advice by clinicians,and the observation group was given medical advice by clinicians.Clinical pharmacists provided pharmaceutical services to patients.The treatment effect,blood pressure compliance rate,hemoglobin compliance rate,serum calcium compliance rate,inflammatory factor level,medication compliance and incidence of adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 92.50％,which was higher than 82.50％in the control group(P＜0.05).The blood pressure compliance rate,hemoglobin compliance rate and serum calcium compliance rate in the observation group were higher than those in the control group(P＜0.05).After intervention,the levels of C-reactive protein(CRP),interleukin(IL-6)and tumor necrosis factor(TNF-α)in the two groups were lower than those before intervention,and those in the observation group were lower than those in the control group(P＜0.05).The good rate of medication compliance in the observation group was 97.50％,which was higher than 85.00％in the control group(P＜0.05).The incidence of adverse reactions in the observation group was 5.00％,which was lower than 15.00％in the control group(P＜0.05).Conclusion Clinical pharmacists participating in individualized administration of anti-infective drugs in patients with renal failure can promote the rationality of administration,reduce the incidence of adverse reactions,improve the therapeutic effect,improve the compliance rate of blood pressure,hemoglobin and serum calcium,and reduce the level of inflammatory factors.
Clinical pharmacistsRenal failureAnti-infective drugsIndividualized administrationPharmaceutical care
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