Analysis of Medication Rules of Traditional Chinese Medicine Enema in the Treatment of Bacillary Dysentery Based on Data Mining
Objective To analyze the prescription rules of traditional Chinese medicine enema in the treatment of bacillary dysentery(BD),and to provide reference for clinical diagnosis and treatment and basic research of the disease.Methods The literature on the treatment of BD by traditional Chinese medicine enema was retrieved from CNKI and other databases.The database was established by using the Traditional Chinese Medicine Inheritance Support System platform,and the medication rules were analyzed.Results There were 47 literatures on the treatment of BD by traditional Chinese medicine enema,including 48 prescriptions available for entry into the system,with 53 flavors of traditional Chinese medicine.The three drugs with the highest frequency of use were Coptis chinensis,Pulsatilla chinensis and Phellodendron amurense.There were 8 drugs with a frequency of more than 10.The high-frequency drugs showed that the efficacy of the drugs was mainly based on clearing heat and drying dampness,clearing heat and detoxifying,clearing heat and cooling blood.Among the traditional Chinese medicines for enema treatment of BD,bitter and cold Chinese medicines and medicines belonging to the large intestine,stomach,spleen and liver were the most widely used.There were 11 commonly used drug combinations,among which Coptis chinensis-Pulsatilla chinensis drug pairs had the highest frequency of occurrence;there are 8 commonly used drug rules,involving 5 traditional Chinese medicines.Four new combinations were obtained by cluster analysis,which were Huangqin-Baishao-Chishao-Gegen-Muxiang,Baitouweng-Qinpi-Huangbo-Dasuan,Diyu-Gengen-Muxiang-Qinpi,Huanglian-Qinpi-Huangbo-Kushen.Conclusion Traditional Chinese medicine enema in the treatment of BD is mainly based on bitter and cold drugs.The prescription idea is mostly the modified Baitouweng decoction,which has good clinical efficacy and research prospects.
Bacillary dysenteryEnemaTraditional Chinese Medicine Inheritance Support SystemData mining
万方数据
维普
