Objective To evaluate the success rate,puncture time and incidence of puncture complications between distal radial artery approach and transradial artery approach in coronary intervention by Meta-analysis.Methods PubMed,EMbase,Cochrane Library,Si-nomed,China National Knowledge Infrastructure(CNKI),Wanfang Data,VIP and other databases were searched by computer.Three researchers independently collected data,and two researchers assessed the data content and used RevMan5.3 software for meta-analysis.Results A total of 12 RCT studies involving 4886 patients were included.Compared with the traditional radial artery puncture approach,the success rate of distal radial artery puncture was lower(OR=6.73,95%CI:4.58-9.90,P<0.000 01,Z=9.69),the success rate of one-time puncture was lower(OR=2.86,95%CI:2.37-3.45,P<0.000 01,Z=10.96),and the puncture time was longer(OR=0.73,95%CI:0.40-1.06,P<0.000 1,Z=4.30),the occlusion rate of distal radial artery approach was lower(OR=0.25,95%CI:0.18-0.35,P<0.000 01,Z=7.98).There was no significant difference in local hematoma(OR=0.88,95%CI:0.64-1.21,P=0.43,Z=0.80)and radial artery spasm(OR=1.00,95%CI:0.62-1.61,P=0.99,Z=0.01)between the two groups.Conclusion Compared with the traditional radial artery approach,the distal radial artery approach has a lower puncture success rate and a longer puncture time during coronary intervention.There is no significant change in the incidence of local hematoma and radial artery spasm,but it can effectively avoid radial artery occlusion.