Effect of Different Pneumoperitoneum Pressure on Liver and Intestinal Function After Laparoscopic Cholecystectomy in Patients with Gallstones
Objective To study the effect of different pneumoperitoneum pressure on liver and intestinal function after laparoscopic cholecystectomy in patients with gallstones.Methods A total of 60 patients with cholecystolithiasis who underwent laparoscopic cholecystectomy in our hospital from March 2020 to March 2023 were selected as the research objects.They were divided into control group and observation group by random number table method,with 30 patients in each group.The observation group was treated with low pneumoperitoneum pressure(8-12 mmHg),and the control group was treated with high pneumoperitoneum pressure(13-15 mmHg).The postoperative pain score(VAS),postoperative gastrointestinal function recovery index(first exhaust,intestinal sound recovery and stool time),hemodynamic index[carbon dioxide partial pressure(PaCO2),mean arterial pressure(MAP)],liver function index[alanine aminotransferase(ALT),aspartate aminotransferase(AST)]and complication rate were compared between the two groups.Results The VAS score of the observation group at 12 and 24 hours after operation was lower than that before operation,and the observation group was lower than the control group(P＜0.05).The time of first exhaust,recovery of bowel sounds and first defecation in the observation group were shorter than those in the control group(P＜0.05).The PaCO2 and MAP at 10 min after pneumoperitoneum in the two groups were higher than those before pneumoperitoneum,but the observation group was lower than the control group(P＜0.05).ALT and AST on the first day after operation in the two groups were higher than those before operation,but there were no significant difference between the observation group and the control group(P＞0.05).The incidence of complications in the observation group was 6.67％,which was lower than 20.00％in the control group(P＜0.05).Conclusion Different pneumoperitoneum pressures have different effects on liver and intestinal function after laparoscopic cholecystectomy in patients with gallstones.Relatively speaking,patients with low pneumoperitoneum pressure(8-12 mmHg)have rapid recovery of gastrointestinal function after operation,and can reduce postoperative pain,reduce the incidence of complications,and reduce the impact on liver function and hemodynamics.
Pneumoperitoneum pressureGallstonesLaparoscopic cholecystectomyLiver and intestinal function
万方数据
维普
