Clinical Effect of Qingre Lishi Decoction Combined with Metronidazole Vaginal Gel in the Treatment of Bacterial Vaginosis and its Effect on Vaginal Local Microenvironment
Objective To analyze the clinical efficacy of Qingre Lishi decoction combined with metronidazole vaginal gel in the treatment of bacterial vaginitis and its effect on vaginal local microenvironment.Methods Sixty patients with bacterial vaginitis diagnosed and treated in our hospital from January 2020 to April 2023 were selected as the research objects.They were divided into control group(n=30)and observation group(n=30)by random number table method.The control group was treated with metronidazole vaginal gel,and the observation group was treated with Qingre Lishi decoction on the basis of the control group.The clinical efficacy,improvement time of clinical symptoms,vaginal local microenvironment(pH value,vaginal flora intensity score),vaginal secretion Nugent score,recurrence rate and incidence of adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 96.67％,which was higher than 83.33％in the control group(P＜0.05).The improvement time of vaginal itching,abnormal leucorrhea,vulvar pain and mucosal congestion in the observation group was shorter than that in the control group(P＜0.05).After treatment,the vaginal pH value and vaginal flora density in the two groups were lower than those before treatment,and those in the observation group were lower than those in the control group(P＜0.05).The Nugent scores of vaginal secretions in the two groups after treatment were lower than those before treatment,and those in the observation group were lower than those in the control group(P＜0.05).After 1 month of follow-up,the recurrence rate of the observation group was 6.67％,which was lower than 16.67％of the control group(P＜0.05).The incidence of adverse reactions in the observation group was 10.00％,compared with 6.67％in the control group,the difference was not statistically significant(P＞0.05).Conclusion Qingre Lishi decoction combined with Metronidazole Vaginal Gel has a good effect in the treatment of bacterial vaginitis,which can effectively improve the clinical symptoms and vaginal local microenvironment,reduce the Nugent score and recurrence rate of vaginal secretions,and does not increase clinical adverse reactions.
Qingre Lishi decoctionMetronidazole vaginal gelBacterial vaginitisVaginal local microenvironment
万方数据
维普
