Effect of Triple Therapy of Carboprost Tromethamine,Ergometrine and Oxytocin on Postpartum Hemorrhage and Uterine Involution in Vaginal Delivery Women
Objective To study the effect of triple therapy of carboprost tromethamine(CTI),ergometrine(EM)and oxytocin(OT)on postpartum hemorrhage and uterine involution in vaginal delivery.Methods From June 2020 to June 2023,80 puerperaes who underwent vaginal delivery in Tianjin Port Hospital were selected as the research objects.They were divided into control group and observation group by random number table method,with 40 puerperaes in each group.The control group was treated with EM combined with OT,while the observation group was treated with triple therapy of CTI,EM and OT.The medication effect,postpartum hemorrhage(2 h after operation,24 h after operation),biochemical indexes[hemoglobin(Hb),proportion of postpartum Hb decrease ≥30 g/L],adverse reactions(gastrointestinal symptoms,dizziness,palpitations,abnormal blood pressure),uterine involution(fundus descent speed,lochia duration)were compared between the two groups.Results The effective rate of the observation group was higher than that of the control group,and the amount of bleeding at 2 and 24 h after operation was less than that of the control group(P＜0.05).The proportion of postpartum Hb decrease ≥30 g/L in the observation group was lower than that in the control group(P＜0.05).The rate of fundus descent in the observation group was higher than that in the control group,and the duration of lochia was shorter than that in the control group(P＜0.05).Conclusion Triple therapy of CTI,EM and OT has a good preventive effect on postpartum hemorrhage in vaginal delivery women,which can reduce the amount of postpartum hemorrhage,reduce Hb loss,accelerate uterine involution,and has high medication safety.
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