Clinical Efficacy and Adverse Reactions of Budesonide Suspension for Inhalation Combined with Ipratropium Bromide Solution for Inhalation in the Treatment of Acute Bronchitis in Children
Objective To observe the clinical efficacy and adverse reactions of budesonide suspension for inhalation combined with ipratropium bromide solution for inhalation in the treatment of acute bronchitis in children.Methods Sixty children with acute bronchitis diagnosed and treated in our hospital from March 2019 to March 2023 were selected as the research objects.They were divided into control group(n=30)and observation group(n=30)by random number table method.The control group was treated with ipratropium bromide solution for inhalation,and the observation group was combined with budesonide suspension for inhalation on the basis of the control group.The clinical efficacy,disappearance time of clinical symptoms(cough,sputum,shortness of breath),pulmonary function indexes[forced vital capacity(FVC),forced expiratory volume in 1 second(FEV1)and peak expiratory flow(PEF)]and incidence of adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 93.33％,which was higher than 80.00％in the control group(P＜0.05).The disappearance time of cough,sputum and shortness of breath in the observation group was shorter than that in the control group(P＜0.05).After treatment,FVC,FEV1 and PEF in the two groups were higher than those before treatment,and those in the observation group were higher than those in the control group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the observation group and the control group(P＞0.05).Conclusion Budesonide suspension for inhalation combined with ipratropium bromide solution is effective in the treatment of acute bronchitis in children,which can improve lung function,promote the rapid disappearance of clinical symptoms,and does not increase the incidence of adverse reactions.It has good application safety and effectiveness.
Budesonide suspension for inhalationIpratropium bromide solution for inhalationAcute bronchitis
万方数据
维普
