Study on the Degree of Arterial Stenosis in Patients with Cerebrovascular Disease and its Correlation with Risk Factors and TCM Constitution
Objective To study the correlation between the degree and distribution of arterial stenosis in patients with cerebrovascular disease and risk factors and TCM constitution.Methods A total of 258 patients with cerebrovascular stenosis confirmed by DSA admitted to Taihe Hospital of Traditional Chinese Medicine Affiliated to Anhui University of Chinese Medicine from October 2020 to October 2022 were selected.The TCM constitution types of the patients were collected by field investigation,and the risk factors and vascular stenosis were statistically analyzed.Results Among the included patients,the proportion of carotid stenosis was higher(49.22％),followed by vertebral artery stenosis(36.43％)and middle cerebral artery stenosis(36.05％).Spearman correlation analysis showed that carotid artery stenosis was positively correlated with phlegm dampness,blood stasis and qi stagnation;vertebral artery stenosis was positively correlated with qi deficiency,and blood stasis;middle cerebral artery stenosis was positively correlated with blood stasis;basilar artery stenosis was positively correlated with phlegm dampness and blood stasis;hypertension was positively correlated with yin deficiency;diabetes was positively correlated with yin deficiency,qi deficiency,phlegm dampness and damp heat;hyperlipidemia is positively correlated with qi deficiency and blood stasis;high HCY was positively correlated with qi deficiency and blood stasis(P＜0.05).Logistic regression analysis showed that age,smoking,drinking,hypertension,diabetes and hyperlipidemia were risk factors for intracranial and extracranial arterial stenosis.The older,smoking and drinking were more likely to have arterial stenosis than those of the younger,non-smokers and non-drinkers.Patients with hypertension,diabetes and hyperlipidemia were more likely to have arterial stenosis than those of non-disease patients.Patients with phlegm dampness and blood stasis in TCM constitution were more likely to have arterial stenosis.Conclusion The degree of arterial stenosis in patients with cerebrovascular disease is related to risk factors and TCM constitution.
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