Effect of Triamcinolone Acetonide Nasal Spray Combined with Endoscopic Sinus Surgery on VAS Score and Nasal Mucociliary Transport Rate in Patients with Chronic Sinusitis and Nasal Polyps
Objective To study the effect of triamcinolone acetonide nasal spray combined with endoscopic sinus surgery on VAS score and nasal mucociliary transport rate in patients with chronic sinusitis and nasal polyps.Methods A total of 60 patients with chronic sinusitis and nasal polyps diagnosed and treated in our hospital from January 2022 to January 2023 were selected as the research objects.They were divided into control group and observation group by random number table method,with 30 patients in each group.The control group was treated with nasal endoscopic surgery combined with normal saline,and the observation group was treated with triamcinolone acetonide nasal spray on the basis of the control group.The therapeutic effect,postoperative nasal cleaning time,pain(VAS)score,nasal mucociliary transport rate,olfactory function,nasal function and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group(96.67％)was higher than that in the control group(83.33％)(P＜0.05).The postoperative nasal cleaning time and VAS score of the observation group were less than those of the control group,and the nasal mucosal cilia transport rate was higher than that of the control group(P＜0.05).The olfactory function score of the two groups after treatment was lower than that before treatment,and that of the observation group was lower than of the control group(P＜0.05).The total nasal airway resistance(NAR)and the distance from the minimum cross-sectional area of the nasal cavity to the anterior nostril(DCAN)in the two groups were lower than those before treatment,and the nasal cavity volume(NCV)and the minimum cross-sectional area of the nasal cavity(NMCA)were higher than those before treatment,while the NAR and DCAN in the observation group were lower than those in the control group,and the NCV and NMCA were higher than those in the control group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the observation group and the control group(P＞0.05).Conclusion Triamcinolone acetonide nasal spray combined with endoscopic sinus surgery is effective in the treatment of chronic sinusitis with nasal polyps,which can improve the therapeutic effect,reduce pain,shorten nasal cleaning time,improve nasal mucociliary transport rate,improve nasal cavity and olfactory function,and does not increase adverse reactions.It is worthy of clinical application.
国家科技期刊平台
NSTL
万方数据
