Effect of Intestinal Microbiota on Immunotherapy of Lung Cancer
The intestinal microbiome is a complex microecosystem in the human body,which is closely related to the occurrence and development of many intestinal and intestinal diseases.In recent years,more and more studies have shown that intestinal microbes play a non-negligible role in the occurrence,development,diagnosis and treatment of lung cancer.Based on the in-depth exploration of the relationship between gut microbiota and gut-lung axis and immune system,this article focuses on its role in affecting the occurrence and progression of lung cancer and immune checkpoint inhibition therapy,and summarizes the current feasible methods to regulate gut microbiota to improve the effect of immunotherapy.At the same time,it also points out that there may be difficulties and challenges,and provides a reference for the application of immune checkpoint inhibitors in the treatment of lung cancer.