Value of Atorvastatin Calcium in Improving the Amount of Bleeding and Neurological Function of Chronic Subdural Hematoma
Objective To observe the value of atorvastatin calcium in improving the amount of bleeding and neurological function of chronic subdural hematoma.Methods A total of 62 patients with chronic subdural hematoma diagnosed and treated in our hospital from May 2019 to May 2023 were selected as the research objects.They were divided into control group and observation group by random number table method,with 31 patients in each group.The control group was given routine symptomatic treatment,and the observation group was treated with atorvastatin calcium on the basis of the control group.The clinical efficacy,the amount of subdural hematoma at different time,neurological deficit score(CSS),activity of daily living scale score(BI),recurrence rate and incidence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group(93.55％)was higher than that of the control group(80.65％)(P＜0.05).After 1 and 2 weeks of treatment,the amount of subdural hematoma in the observation group was less than that in the control group(P＜0.05).The CSS score of the two groups was lower than that before treatment,and that of the observation group was lower than that of the control group(P＜0.05).The BI score of the two groups was higher than that before treatment,and that of the observation group was higher than that of the control group(P＜0.05).After 2 months of follow-up,the recurrence rate of the observation group(3.23％)was lower than that of the control group(16.13％)(P＜0.05).There was no significant difference in the incidence of adverse reactions between the observation group and the control group(P＞0.05).Conclusion Atorvastatin calcium has a significant effect in the treatment of chronic subdural hematoma,which can improve the therapeutic effect,reduce the amount of bleeding,improve the neurological deficit and activities of daily living,reduce the recurrence rate,and do not increase the risk of adverse reactions.It is worthy of clinical application.
Atorvastatin calciumChronic subdural hematomaThe amount of bleedingNeurological function
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维普
