Analysis of the Efficacy and Safety of Endoscopic Mucosal Resection in Patients with Gastrointestinal Polyps
Objective To study the therapeutic effect and safety of endoscopic mucosal resection(EMR)in patients with gastrointestinal polyps.Methods A total of 60 patients with gastrointestinal polyps diagnosed and treated in our hospital from January to October 2023 were selected as the research objects.They were divided into control group(n=30)and study group(n=30)by random number table method.The control group was treated with ordinary endoscopic electrocoagulation,and the study group was treated with EMR.The polyp resection,clinical operation indexes(polyp resection time,operation time,bleeding volume,postoperative feeding time,hospitalization time),inflammatory factors levels[procalcitonin(PCT),interleukin-6(IL-6),C-reactive protein(CRP),interleukin-17(IL-17)],gastrointestinal hormones levels(motilin,gastrin)and complication rate were compared between the two groups.Results The complete resection rate of polyps in the study group was 96.67％,which was higher than 80.00％in the control group(P＜0.05).The polyp resection time,operation time and postoperative feeding time in the study group were shorter than those in the control group,and the amount of bleeding was less than that in the control group(P＜0.05).There was no significant difference in hospitalization time between the two groups(P＞0.05).The levels of PCT,IL-6,CRP and IL-17 in the two groups after operation were higher than those before operation,and those in the study group were lower than the control group(P＜0.05).The levels of motilin and gastrin in the two groups were lower than those before operation,but those in the study group were higher than those in the control group(P＜0.05).The incidence of complications in the study group was 6.67％,which was lower than 16.67％in the control group(P＜0.05).Conclusion EMR can improve the complete resection rate of polyps in patients with gastrointestinal polyps,reduce the body's inflammatory stress and gastrointestinal stress response,shorten the operation and polyp resection time,reduce intraoperative blood loss,and reduce the incidence of complications.It is worthy of clinical application.
万方数据
维普
