Clinical Value of Combined Detection of Serum AFP,CEA and CA199 in the Differential Diagnosis of Hepatitis C-related Cirrhosis and Liver Cancer
Objective To study the clinical value of combined detection of serum alpha-fetoprotein(AFP),carcinoembryonic antigen(CEA)and carbohydrate antigen 199(CA199)in the differential diagnosis of hepatitis C-related cirrhosis(HCV-Cirr)and liver cancer(LC).Methods A total of 48 patients with HCV-Cirr admitted to Shicheng County People's Hospital from October 2021 to April 2023 were selected as the HCV-Cirr group,and 14 patients with LC diagnosed at the same time were selected as the LC group.The levels of serum AFP,CEA and CA199 were compared between the two groups.The positive detection rates of serum AFP,CEA and CA199 alone and combined detection in HCV-Cirr and LC were counted.Then the differential diagnostic value of serum AFP,CEA and CA199 alone and combined detection in HCV-Cirr and LC was analyzed and compared.Results The levels of serum AFP,CEA and CA199 in LC group were higher than those in HCV-Cirr group(P＜0.05).The HCV-Cirr positive detection rate and LC positive detection rate of combined detection of serum AFP,CEA and CA199 were higher than those of single detection(P＜0.05).The accuracy,sensitivity and specificity of combined detection of serum AFP,CEA and CA199 in the differential diagnosis of HCV-Cirr and LC were higher than those of single detection(P＜0.05).Conclusion Serum AFP,CEA and CA199 indicators have a definite diagnostic effect in the detection of HCV-Cirr and LC,and the combined detection of the three has a higher differential diagnostic value.
万方数据
维普
