Research Status of Triple-negative Breast Cancer Related Targets
Triple-negative breast cancer(TNBC)is the most aggressive subtype of breast cancer with high malignancy.Due to the lack of effective diagnosis and treatment,lack of specific targets and targeted therapy,multidrug resistance and other factors,the current available treatment methods have a significantly poor effect in the treatment of TNBC.BRCA1/2,TLR3,CDKN2A,IFNG,ACSS2,IRS2,ZNF33A,etc.are common genes associated with triple-negative breast cancer.This article reviews the related targets of TNBC diagnosis,prognosis prediction,treatment,drug resistance and the gene delivery system of TNBC,in order to provide ideas for clinical treatment and drug development.
Triple-negative breast cancerDiagnosis and prognosisGene therapyDrug resistance
万方数据
维普
