Discussion on the Rule of Syndrome Differentiation and Treatment of Advanced Lung Cancer by Traditional Chinese Medicine Based on Data Mining
Objective To explore the rule of syndrome differentiation and treatment and prescription medication of traditional Chinese medicine in the treatment of advanced lung cancer.Methods Through the Medcase V5.2 warehouse public medical record data mining system,frequency analysis and association rule analysis were used to mine the medical records of advanced lung cancer treated with traditional Chinese medicine in the oncology department of Yancheng Hospital of Traditional Chinese Medicine from 2016 to 2020 from the aspects of symptoms,etiology,pathogenesis and prescription medication.Results A total of 171 patients with 587 visiting times were included,including 120 males and 51 females.The clinical manifestations of patients with advanced lung cancer mainly include cough,easy to wake up,difficulty in falling asleep,loss of appetite,fatigue,less phlegm,phlegm stickiness,white phlegm,asthma,constipation and so on.the tongue manifestations in higher frequencies were pale red tongue,red tongue,white slimy fur,fur deficiency,thin white fur and light tongue;the pulse conditions in higher frequencies were fine pulse,string-like pulse,slippery pulse,weak pulse and sunken pulse;the pathogenesis was deficiency of both Qi and Yin,cancer toxin depressed lung,phlegm dampness accumulation in lung,deficiency fire burning internal,lung dehydration and depression,deficiency of lung and spleen Qi,lung loss of consciousness and sobriety,phlegm stasis obstructing lung,phlegm retention accumulation in lung and spleen deficiency failing in transportation;the common drugs were Fuling,Shenghuangqi,Shenggancao,Fabanxia,Chenpi,Maidong,Baihe,Chaobaizhu,Baihuasheshecao,Dangshen,Danggui,Wuweizi,Shudihuang,Fengfang,Xuanshen and others successively.Among the clinical symptoms,cough-fatigue,cough-difficulties in falling asleep,and cough-loss of appetite are closely related.The commonly used pathogenesis combinations were lung and spleen qi deficiency-phlegm-dampness accumulation in lung,lung and spleen qi deficiency-phlegm retention in lung,lung loss of moistening and descending-deficiency of both qi and yin.The pathogenesis of lung and spleen qi deficiency-phlegm-dampness accumulation in lung was closely related to the clinical symptoms of difficulty in falling asleep and easy to wake up.Conclusion The clinical symptoms of advanced lung cancer are mainly local symptoms of the lung,and systemic symptoms such as diet,sleep,and stool are not uncommon.The pathogenesis focuses on the deficiency of both qi and yin,and the characteristic pathogenesis is cancer toxin obstructing lung.The disease location involves lung,spleen,heart,kidney and other organs,and the etiology involves phlegm,dampness,blood stasis,drinking,heat,qi and cancer toxin.In the treatment,the treatment method is formulated according to the core pathogenesis.Yiqi Yangyin is the core treatment method.Anti-cancer detoxification runs through the whole process.Phlegm,dampness,stasis,heat,and qi are used in combination.The lung and spleen are not treated alone.It can also be treated from the heart and kidney.A variety of drugs are used in combination to increase the efficacy.
Advanced lung cancerTraditional Chinese medicineThe rules of treatment differentiation