Comparative Analysis of Three Pathogen Detection Methods for Mycoplasma Lobar Pneumonia in Children
Objective To study the early laboratory examination results of lobar pneumonia caused by Mycoplasma pneumoniae infection,and to explore the predictive value of related indicators.Methods The laboratory test results of children with lobar pneumonia caused by suspected mycoplasma pneumoniae infection admitted to the Second Affiliated Hospital of Nanjing Medical University from January to August 2023 were retrospectively analyzed.The significance of three mycoplasma pathogens and serological detection methods in the early diagnosis of mycoplasma lobar pneumonia in children was analyzed.Results The positive detection rate of MP by nucleic acid detection method was the highest,the positive detection rates of MP by chemiluminescence method,indirect immunofluorescence method and nucleic acid detection method were 37.78％,28.89％and 82.22％,respectively,the consistency of the three detection methods was poor,and the Kappa values of pairwise comparison were 0.089,-0.444 and-0.533,respectively.There was a statistically significant difference in the results of MP detection by chemiluminescence in children of different genders(P＜0.05).Conclusion Simultaneous nucleic acid and antibody detection is helpful for early and accurate diagnosis of mycoplasma pneumonia in children,and provides a basis for early diagnosis and treatment of the disease.
万方数据
维普
