Effect of Midazolam Combined with Brachial Plexus Anesthesia in Upper Limb Fracture Surgery and its Effect on Cognitive Function
Objective To study the effect of midazolam combined with brachial plexus anesthesia in upper limb fracture surgery and its effect on cognitive function.Methods A total of 67 patients who underwent upper limb fracture surgery in our hospital from June 2021 to January 2023 were selected as the research objects.They were divided into control group(n=34)and observation group(n=33)by random number table method.The control group was treated with brachial plexus anesthesia,and the observation group was treated with midazolam combined with brachial plexus anesthesia.The clinical anesthesia effect(onset time and duration of anesthesia and motor block),Mini-mental State Examination(MMSE)score,Ramsay sedation score,pain score(VAS),dynamic indexes at different time periods(heart rate,mean arterial pressure,oxygen saturation)and incidence of adverse reactions were compared between the two groups.Results The onset time of anesthesia and motor block in the observation group was shorter than that in the control group,and the duration of anesthesia and motor block was longer than that in the control group(P＜0.05).The MMSE score of the two groups on the first day after operation was lower than that before operation,the Ramsay score was higher than that before operation,but the MMSE score of the observation group was higher than that of the control group,the Ramsay score was lower than that of the control group(P＜0.05).The postoperative VAS score of the two groups was lower than that before operation,and that of the observation group was lower than that of the control group(P＜0.05).The heart rate,mean arterial pressure and blood oxygen saturation of the two groups after anesthesia were lower than those before anesthesia,but those of the observation group were higher than those of the control group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the observation group and the control group(P＞0.05).Conclusion Midazolam combined with brachial plexus anesthesia in upper limb fracture surgery has good effect,short onset time of anesthesia and motor block,little effect on cognitive function and hemodynamics,and will not increase the incidence of adverse reactions.
Upper limb fracture surgeryMidazolamBrachial plexus anesthesiaAnesthetic effectCognitive function
万方数据
维普
