Clinical Efficacy and Safety of Xiao'er Resuqing Granules Combined with Compound Paracetamol and Methylephedrine Oral Solution in the Treatment of Upper Respiratory Tract Infection with Fever in Children
Objective To analyze the application effect and safety of Xiao'er Resuqing granules combined with compound paracetamol and methyl ephedrine oral solution in children with upper respiratory tract infection and fever.Methods A total of 82 children with upper respiratory tract infection and fever who were treated in Ruijin Maternal and Child Health Hospital from September 2021 to September 2023 were selected and divided into observation group and control group by random number table method,with 41 children in each group.The control group was treated with compound paracetamol and methyl ephedrine oral solution alone,and the observation group was treated with Xiao'er Resuqing granules combined with compound paracetamol and methyl ephedrine oral solution.The clinical efficacy,body temperature changes,inflammatory factor levels,family satisfaction and clinical symptom improvement were compared between the two groups.Results The body temperature of the two groups decreased after 24,48 and 72 h of treatment,and the decrease of the observation group was more than that of the control group(P＜0.05).The total effective rate of the observation group was higher than that of the control group after 72 hours of treatment(P＜0.05).The disappearance time of fever,nasal congestion,runny nose and cough in the observation group was shorter than that in the control group(P＜0.05).The incidence of adverse reactions in the observation group was lower than that in the control group(P＜0.05).The satisfaction of family members in the observation group was higher than that in the control group(P＜0.05).After treatment,the levels of CRP,IL-6 and WBC in the observation group were lower than those in the control group(P＜0.05).Conclusion For children with upper respiratory tract infection and fever,Xiao'er Resuqing granules combined with compound paracetamol and methyl ephedrine oral solution can rapidly reduce the body temperature and inflammatory factor levels,improve the clinical symptoms,with less adverse reactions and high satisfaction of children's families.
Xiao'er Resuqing granulesCompound paracetamol and methylephedrine oral solutionUpper respiratory tract infection with fever in childrenSecurity
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